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Niaspan for High Cholesterol User Reviews

Niaspan has an average rating of 5.8 out of 10 from a total of 24 reviews for the treatment of High Cholesterol. 46% of reviewers reported a positive experience, while 25% reported a negative experience.

Niaspan rating summary

5.8/10 average rating

24 ratings from 26 user reviews.

Compare all 295 medications used in the treatment of High Cholesterol.

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25%
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4%
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8%
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Reviews for Niaspan

  • Train...
  • July 29, 2013

"Age 51. Went to get my regular bloodwork with my Doctor. My cholestral has always been >200 and have a family history of Heart Attack and stroke. I tried everything over the years including Crestor which was an absolute disaster for me after only 4 doses. Since then tried the natural methods Red Yeast Rice (may as well be on a statin the side effects are basically the same) and lots of fish and Krill oil. I was disappointed that my bad cholesterol was high after all that still and my number was 219 total. Based on my unwillingness to try another Statin my Dr. suggested a 500mg pill of Niaspan to be taken nightly. I have experienced no flushing as yet after a month on it and really no bad side effects. New blood results 192! Will check back in 3 mos."

8 / 10
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59 Report
  • Ashleyp
  • December 21, 2010

"We believe this medication Niaspan has caused liver failure in our father, that is what the Doctors told us so please anyone on this please have your liver function tested. It is easily doe by a blood test."

1 / 10
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61 Report
  • BeeJa...
  • April 7, 2011

"I have taken Niaspan 2000 mg for several years now. It has had great success in raising my HDL and keeping my triglycerides low. For years, I had minimal problems with flushing. But now recently, I have had a number of episodes where I have woken up in the middle of the night with almost unbearable itching/burning skin. I took a break from the Niaspan for a couple nights, and then when I tried it again the itching was worse. I am going to have to discontinue this and consult with my doctor about what to do next to keep my numbers good."

5 / 10
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52 Report

Frequently asked questions

  • Anonymous
  • Taken for 2 to 5 years
  • April 29, 2012

"Problems with flushing until doctor told me not to eat strawberries or chocolate in the evening. I can eat them before lunch. I take Niaspan on going to bed. I eat 2 Graham crackers and 8 oz of milk when I take it. This has resolved all my problems with the medicine."

6 / 10
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41 Report
  • printer...
  • Taken for 2 to 5 years
  • April 23, 2013

"I take 1000mg two times a day. Taking 325 mg aspirin before I take the Niaspan helps with the flushing. I have been on Niaspan for about 3 years now, my numbers are down 10%. The little bit of flushing I do get is a lot better than the severe joint pain I had with the statin medications. I recommend taking Niaspan. It is working for me."

9 / 10
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36 Report

Are you taking this medicine?

  • baby...
  • March 19, 2013

"Woke up and felt like I was on fire. Skin was red and my heart was pounding. Nauseated and very itchy. Calling my doctor in the morning. It is not worth it. This has happened twice but this time it is worse. Feel very sick from it. My skin is so red."

3 / 10
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36 Report
  • Jessi...
  • October 15, 2009

"I participate in a Niaspan clinical trial and take 2000mg/day along with Zocor and Zetia. I'm 65 and have severe arteriosclerosis. This combination of drugs has made a dramatic difference in my cholesterol numbers. I find that I don't have the "flushing" (actually more like BURNING) if I take the Niaspan EVERY night and follow the asperin, applesauce and wheat crackers technique. It's rather a hassle but I think worth the trouble."

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40 Report
  • lov
  • August 19, 2009

"I started on Niaspan for 2 months 500 at night. I had no problems at all. I took an asprin 1/2 hr. before then ate a snack, cottage cheese and never had no flushing, or anything. I was to take two 500 a night. But when I checked the price at WalMart they was $15?.00 for a 30 day supply. I just bought the flush free Niacin been taking them now for a week and still no flushing, or felt no different. I have no problems so far with them. Soon as I have my blood test again I will let you know how they did for me."

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38 Report
  • Anonymous
  • September 19, 2011

"When major diet changes and exercise hardly changed cholesterol at all I was started on 1500mg Niaspan. I do experience flushing, several times a month. Wake up hot and feel like I am burning up and itchy all over. If it delays another heart attack like 14 years ago it is a small price to pay."

9 / 10
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33 Report
  • Train...
  • Taken for 1 to 2 years
  • July 16, 2014

"Posted about a year ago here after I first started a 500 mg nightly regimen of Niaspan. For awhile it appeared as though I would not have the usual side effect of burning skin. However, the Acid reflux I began experiencing began to worsen over time along with gastric problems at night. Then as an active person who is involved in teaching Cardio Boxing classes I began to experience weird feelings in my chest along with a more pronounced heart beat during and after exercise. Felt like I swallowed a Basketball at times. Also could not have any alcohol Beer or Wine while taking this. I decided to stop taking it in fear of creating an Arrythmyia or Stroke during my exercise which also is my Job. This is day one off of it and feel better."

4 / 10
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23 Report
  • Anonymous
  • January 16, 2011

"Went on Niacin @ 8000mg fifteen years ago. Now on Niaspan @ 2000mg for last five years. First medicine that has worked well with my body. My HDL stays in the 70s and total Cholesterol under 120. Dosing time and other foods have to be managed to suppress flushing. "

8 / 10
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29 Report
  • Lola
  • Taken for 10 years or more
  • December 29, 2018

"I took maximum dose of Niaspan for over ten years. The drug raised the uric acid levels in my body and gave me horrible gout attackā€™s and raised my blood sugar levels to prediabetic. Do not take this drug."

2 / 10
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13 Report
  • Anonymous
  • August 4, 2009

"After a few days of taking this medication, I was awoken in the middle of night with the the warm red rash on my abdomen which was also extremely itchy. After 3 consecutive nights of the same reaction, I discontinued the medicine and called my doctor. He changed my prescription to another cholesterol medicine."

5 / 10
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25 Report
  • bewitch
  • February 13, 2011

"I've been on Niaspan for about 2 months, and its has been like a miracle medicine for my condition. I suffer with ulcers really bad on my fingers. Before starting the Niaspan I had ulcers on every finger on both hands (very, very, painful), was on pain medicines constantly, however I'm now off the pain medicines since last week, ulcers are drying up tremendously. The flushing is awful, the burning, and itching is hard to describe. I called my doctor and he said we can try something else, but this is working and I'm trying to hang with it. "

8 / 10
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22 Report
  • GLAD...
  • Taken for less than 1 month
  • March 18, 2014

"Niaspan was prescribed by my doctor for Lipid Protein little a. My cholestrol was about 400+. I took one dose (500mg) at night and within 30 minutes I was in emergency room with anaphylactic shock. I don't remember much of anything till I woke up the next morning and was told how bad it almost was for me. I take 8 statins to maintain a cholesterol of 200."

1 / 10
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17 Report
  • Train...
  • Taken for 6 months to 1 year
  • July 18, 2014

"Off it completely for 2 days now. Acid reflux much better and more importantly no Pronounced heart beats or racing. Feeling normal again thank God. I truly believe after my experience with both Niaspan and Crestor is that they actually starve your heart of the Oxygen it needs if your an athlete. Heart rate problems or potential Arrhythmia's may not be revealed in people who have more sedentary lifestyles. The fact that the new recommendation is to stack COQ10 with the statins should prove that they can rob your heart of energy when you work it hard during intense exercise. "

4 / 10
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14 Report
  • Tiko
  • Taken for 2 to 5 years
  • November 16, 2019

"I have taken Niaspan 1000 mg for several years now. It has had great success in raising my HDL (from 31 to 39) and keeping my triglycerides low. First time I took it my heart rate went up to 160, I went to emergency room not knowing what is going on with my heart, heart rate came down in hour. No problem since then, I take it with Milk and mix cereal. I tried to stop it for six months and my HDL gone Low to 34 and my triglycerides gone high 203."

9 / 10
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8 Report
  • Anonymous
  • November 24, 2010

"Been taking time release 2000mg at night for three years now, don't know why it's so expensive but it's the only thing that has ever raised my good cholesterol. If I wake up in the middle of the night, I do have the heat feelings but can live with it. Whatever raises my good cholesterol is the best I can do, since it's so low!"

9 / 10
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16 Report
  • badta
  • October 27, 2010

"I've been taking it for five years now. I've only had one episode of flushing since starting this medication. I took a Zantac at the same time as the 2000mg Niaspan and I woke up feeling like I was on fire. But I've had no problems since then."

10 / 10
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13 Report
  • Jan
  • Taken for 5 to 10 years
  • February 27, 2019

"I have been taking Niaspan 2000 for the last 8 years with ok results. But the last time I went to the Dr. my cholesterol was 220. The Dr put me on Zetia since I cannot take statins. Unfortunately Zetia had the same reaction on my body as statins. Terrible joint pain. After only 10 days I had to stop. I was hoping it would be the answer but it wasn't. I went back on Niaspan. I watch what I eat and have been a vegetarian for 45 years. Dr said it was hereditary that my liver makes too much cholesterol and it was not my diet. I am at the end of my rope now if the Niaspan stops working. Suggestions?"

7 / 10
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6 Report
  • Frank...
  • August 2, 2017

"Had high Triglycerides for more than a decade. Was on Niaspan for much of that time. Little or no impact on my numbers (continually had 400 level Triglycerides or higher) My daughter, a nursing student, suggested I look at something different. Finally moved to Lopid. Take 1 pill when I wake up, and one 30 minutes before my evening meal. Since taking Lopid, I've not had a number higher than 150, and I'm eating what I want. I realize that Niaspan might work for some. But if it's not working for you, I strongly recommend trying Lopid."

1 / 10
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7 Report
  • 42ano
  • January 16, 2015

"I have been taking 1500 mg at bedtime for about 4 years. It has lowered my cholesterol some but I'm also taking Zetia and Crestor too at this time. (I have Familial High Cholesterol about 380) I have flushing, but it is mild compared to regular Niacin which I could never tolerate. Flushing is worse if I forget and skip a day. Drinking water helps with the flushing."

8 / 10
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5 Report
  • Anonymous
  • June 24, 2009

"I've been on it for about 10 days now and it seems to be working well. "

8 / 10
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28 Report
  • Anonymous
  • May 2, 2009

"Seemed to work okay for me."

8 / 10
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25 Report
  • Anonymous
  • September 25, 2011

"Lowered my cholesterol but after 6 weeks I had to discontinue due to hives."

1 / 10
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17 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.